April 27, 2023

Program Agenda

Registration 9:00 AM to 09:15 AM

Focus 1 9:15 AM TO 10:30 AM

Amyloid proteins

Dr Jehan Waeytens – ULB - “Infrared nano spectroscopy a new tool to study amyloid fibrils”

Dr Karine Goraj – Amyl Therapeutics - Rational design of AML therapeutic agents for specific binding and clearance of diverse amyloid aggregates

Prof. Sofie Nyström – Linköping Universtiy - Understanding amyloids using fluorescence analysis”

Coffee Break 10:30 AM TO 11:00 AM

FOCUS 2 11:00 AM TO 12:45 PM

Glycosylation

Dr Catherine Ronin – Siamed’Xpress - Using glycosylation as a barcode to produce better and safer antibodies”

Dr Paul Wassmann – Novartis - Analytical challenges in pharmaceutical industry”

Dr Allison Derenne – Spectralys Biotech - A new convenient tool to analyse protein glycosylation based on FT-IR spectroscopy

Prof. Cédric Delporte – ULB - Online SPE purification followed by LC-fluorescence-MS detection for N-glycan analysis”

Lunch 12:45 PM TO 02:00 PM

sponsors 02:00 PM TO 02:30 PM

Flash presentation

Eng. Hanne Hoskens – Bruker
Dr Amandine Gontier – Dynamic Biosensors
Dr Pierre Soule – NanoTemper
FOCUS 3 02:30 PM to 03:45 PM

Differential Scanning Fluorimetry

Dr Maria Garcia – EMBL Hambourg - DSF and its application in sample optimisation, unfolding screening and determination of binding constants”

Dr Thomas Bertrand – Sanofi - nanoDSF: a key technology for the development of drugs in Industry”

Dr Marylène Vandevenne – Uliège - Automated protein formulation, using the Robotein® high throughput facility”

Coffee Break 03:45 PM TO 04:15 PM

FOCUS 4 04:15 PM to 05:30 PM

Adeno-Associated Virus

Eng. Damien Mouvet – Quality Assistance - "Physico-chemical characterization of AAV”

Dr Stéphanie Hambye – Exothera - Assessing full and empty particles when producing AAV. Is A Ex-HPLC the emerging orthogonal tool to assess this CQA ?”

Dr Bertrand Raynal – Institut Pasteur - Analytical ultracentrifugation: A powerful tool for the quality control of AAV vectors used in gene therapy”

Reception 05:30 PM TO 07:00 PM

AQS³pro demo by RedShiftBio